Adenosine and Clinical Forms of Neurally-Mediated Syncope.
نویسندگان
چکیده
Maggie P.Y. Lam, PhD Vidya Venkatraman, MSc Quan Cao, MD, PhD Ding Wang, PhD T. Umut Dincer, MSc Edward Lau, PhD Andrew I. Su, PhD Yi Xing, PhD Junbo Ge, MD *Peipei Ping, PhD yJennifer E. Van Eyk, PhD *National Institutes of Health BD2K Center of Excellence for Biomedical Computing at UCLA National Heart, Lung, and Blood Institute Proteomics Center at UCLA David Geffen School of Medicine at UCLA University of California, Los Angeles 675 Charles East Young Drive MRL Building, Suite 1-619 Los Angeles, California 90095 E-mail: [email protected] OR yAdvanced Clinical Biosystems Research Institute Cedars-Sinai Medical Center Advanced Health Sciences Pavilion 127 South San Vicente Boulevard Los Angeles, California 90048 E-mail: [email protected]
منابع مشابه
Adenosine test in the diagnosis of unexplained syncope: marker of conducting tissue disease or neurally mediated syncope?
Adenosine test (supine administration of a 20 mg intravenous bolus with electrocardiographic and blood pressure monitoring) has been endorsed by the European Society of Cardiology guidelines on syncope management as an 'experimental' test in the diagnosis of unexplained syncope. The test is quick and cheap, but there is no consensus as to what condition, if any, the adenosine test is exposing, ...
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AIMS We prospectively correlated the results of tilt testing (TT) and adenosine triphosphate test (ATP) with the findings observed during a spontaneous syncopal relapse by means of an implantable loop recorder (ILR) in patients with a clinical diagnosis of neurally mediated syncope. METHODS AND RESULTS We included patients with three or more clinically severe syncopal episodes in the last 2 y...
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BACKGROUND Tilt testing is used to establish the diagnosis of neurally mediated syncope. However, applicability of the tilt test is limited by test sensitivity and length of time required to perform the test. We hypothesized that adenosine could facilitate the induction of neurally mediated syncope through its sympathomimetic effects and therefore could be used as an alternative to routine tilt...
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Neurally-mediated syncope has a broad clinical spectrum which ranges from typical vasovagal syncope on one hand, to those situations in which reflex syncope occurs with uncertain, or even apparently absent, triggers or prodromes, on the other hand. Overlap of clinical features is frequent in clinical practice and makes any classification difficult to apply when selecting patients for cardiac pa...
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BACKGROUND An association between Brugada syndrome and neurally mediated syncope has been described. Although mutations in SCN5A have been identified in Brugada syndrome, the genetic link between Brugada syndrome and neurally mediated syncope has not been determined. OBJECTIVES The purpose of the study was to clinically and genetically characterize a man with recurrent syncope that originally...
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AIMS The clinical effects of different modalities of treatment for neurally mediated syncope have been studied for years; however, their influences on its pathophysiological mechanisms still have not been determined. This research aimed to observe the effects of physical training, tilt training, and pharmacological therapy on the arterial baroreflex sensitivity and muscle sympathetic nerve acti...
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ورودعنوان ژورنال:
- Journal of the American College of Cardiology
دوره 66 2 شماره
صفحات -
تاریخ انتشار 2015